![]() ![]() Eleven preclinical studies (in vitro and animal), fourteen case reports/series, and one human volunteer study were included. Reports on fomepizole as a therapeutic adjunct for APAP toxicity span heterogeneous types of evidence. The objective is to comprehensively review the literature on fomepizole as a potential adjunct antidote for acetaminophen toxicity.Ī scoping review was performed using standardized search terms from inception through July 2021. While N-acetylcysteine (NAC) is an effective antidote, it has therapeutic limitations in massive overdose or delayed presentation. Acetaminophen (paracetamol, APAP) poisoning is a prominent global cause of drug-induced liver injury.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |